E3 ubiquitin-protein ligase MIB1
GPTKB entity
Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:MIB1
Mind bomb-1 |
| gptkbp:associatedWith |
intellectual disability
cardiomyopathy |
| gptkbp:biologicalProcess |
cell differentiation
protein ubiquitination |
| gptkbp:domain |
RING-type zinc finger
Ankyrin repeat |
| gptkbp:encodedBy |
MIB1 gene
|
| gptkbp:enzymeCommissionNumber |
EC 2.3.2.27
|
| gptkbp:function |
E3 ubiquitin ligase activity
Notch signaling pathway regulation |
| gptkbp:gene |
gptkb:MIB1
|
| https://www.w3.org/2000/01/rdf-schema#label |
E3 ubiquitin-protein ligase MIB1
|
| gptkbp:interactsWith |
gptkb:DLL1
gptkb:NOTCH1 gptkb:JAG1 |
| gptkbp:locatedOnChromosome |
18q11.2
|
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:molecularWeight |
110 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
gptkb:Mib1
|
| gptkbp:UniProtID |
Q86YT6
|
| gptkbp:bfsParent |
gptkb:MIB1_(human_gene)
|
| gptkbp:bfsLayer |
7
|