E2 reaction

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:chemical_compound
elimination reaction
gptkbp:commonBases strong bases
gptkbp:compatibleWith carbocation intermediate
gptkbp:competitor gptkb:E1_reaction
SN2 reaction
gptkbp:doesNotProceedThrough carbocation intermediate
gptkbp:example hydroxide ion
potassium tert-butoxide
sodium ethoxide
gptkbp:exampleSubstrate 1-bromobutane
2-bromopropane
gptkbp:favoredBy strong base
weak base
steric hindrance
polar aprotic solvent
poor leaving group
gptkbp:has_stereochemistry anti-periplanar elimination
https://www.w3.org/2000/01/rdf-schema#label E2 reaction
gptkbp:mechanismOfAction bimolecular elimination
gptkbp:mechanismStep single step
gptkbp:namedFor second-order elimination
gptkbp:productStereochemistry gptkb:Hofmann_product_(with_bulky_base)
gptkb:Zaitsev's_rule
gptkbp:productType alkene
gptkbp:rateDependsOn base concentration
substrate concentration
gptkbp:rateLaw second order
gptkbp:requires good leaving group
gptkbp:substrate alkyl halides
gptkbp:transitionState concerted
gptkbp:bfsParent gptkb:Zaitsev_elimination
gptkbp:bfsLayer 7