Zaitsev elimination

GPTKB entity

Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:chemical_compound
gptkbp:alsoKnownAs gptkb:Saytzeff_elimination
gptkbp:appliesTo alkyl halides
alcohols (after activation)
gptkbp:commonIn alkyl halide elimination
gptkbp:competitor substitution reactions
gptkbp:firstDescribed 1875
https://www.w3.org/2000/01/rdf-schema#label Zaitsev elimination
gptkbp:influencedBy gptkb:temperature
solvent
base strength
leaving group ability
steric hindrance
gptkbp:lessFavoredBy bulky base
gptkbp:mechanismOfAction base abstracts proton
leaving group departs
gptkbp:moreFavoredBy small base
gptkbp:namedAfter gptkb:Alexander_Zaitsev
gptkbp:opposedBy gptkb:Hofmann_elimination
gptkbp:productPreference more substituted alkene
gptkbp:regioselectivity favors more substituted double bond
gptkbp:requires acid or base (for E1)
strong base (for E2)
gptkbp:type gptkb:E1_reaction
gptkb:E2_reaction
elimination reaction
gptkbp:yield gptkb:minor_product_(Hofmann_product)
alkene
major product (Zaitsev product)
gptkbp:bfsParent gptkb:Hofmann_elimination
gptkbp:bfsLayer 6