Hofmann product (with bulky base)
GPTKB entity
Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
organic chemistry concept
|
| gptkbp:commonIn |
alkyl halide elimination
quaternary ammonium salt elimination |
| gptkbp:contrastsWith |
Zaitsev product
|
| gptkbp:defines |
The less substituted alkene formed as the major product in an elimination reaction using a bulky base.
|
| gptkbp:example |
triethylamine
potassium tert-butoxide lithium diisopropylamide (LDA) |
| gptkbp:favoredBy |
steric hindrance
|
| gptkbp:formedBy |
elimination of a leaving group from a substrate with a bulky base
|
| https://www.w3.org/2000/01/rdf-schema#label |
Hofmann product (with bulky base)
|
| gptkbp:majorProductIn |
E2 elimination with tert-butoxide
|
| gptkbp:mechanismOfAction |
gptkb:E2_elimination
|
| gptkbp:namedAfter |
gptkb:August_Wilhelm_von_Hofmann
|
| gptkbp:opposedBy |
Zaitsev product
|
| gptkbp:productType |
less substituted alkene
|
| gptkbp:relatedTo |
alkene
elimination reaction bulky base E2 mechanism |
| gptkbp:bfsParent |
gptkb:E2_elimination
|
| gptkbp:bfsLayer |
7
|