Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:biologicalProcess |
gene silencing
epigenetic regulation |
gptkbp:catalyzes |
trimethylation of histone H3 at lysine 27 (H3K27me3)
|
gptkbp:component |
gptkb:Enhancer_of_zeste_[E(z)]
gptkb:Extra_sex_combs_(Esc) Nurf55 (p55) Suppressor of zeste 12 [Su(z)12] |
gptkbp:discoveredIn |
gptkb:Drosophila_melanogaster
|
gptkbp:fullName |
Drosophila Polycomb Repressive Complex 2
|
gptkbp:function |
histone methyltransferase
|
gptkbp:GO_term |
GO:0006342 (chromatin silencing)
GO:0016573 (histone methylation) |
https://www.w3.org/2000/01/rdf-schema#label |
Drosophila PRC2
|
gptkbp:inhibitedBy |
transcription
|
gptkbp:interactsWith |
gptkb:Polycomb_group_proteins
|
gptkbp:locale |
gptkb:nucleus
|
gptkbp:organism |
gptkb:Drosophila_melanogaster
|
gptkbp:orthologIn |
mammalian PRC2
|
gptkbp:regulates |
Hox gene expression
|
gptkbp:requires |
maintenance of repressed chromatin state
|
gptkbp:bfsParent |
gptkb:Polycomb_Repressive_Complex_2
|
gptkbp:bfsLayer |
8
|