Drosophila PRC2

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:biologicalProcess gene silencing
epigenetic regulation
gptkbp:catalyzes trimethylation of histone H3 at lysine 27 (H3K27me3)
gptkbp:component gptkb:Enhancer_of_zeste_[E(z)]
gptkb:Extra_sex_combs_(Esc)
Nurf55 (p55)
Suppressor of zeste 12 [Su(z)12]
gptkbp:discoveredIn gptkb:Drosophila_melanogaster
gptkbp:fullName Drosophila Polycomb Repressive Complex 2
gptkbp:function histone methyltransferase
gptkbp:GO_term GO:0006342 (chromatin silencing)
GO:0016573 (histone methylation)
https://www.w3.org/2000/01/rdf-schema#label Drosophila PRC2
gptkbp:inhibitedBy transcription
gptkbp:interactsWith gptkb:Polycomb_group_proteins
gptkbp:locale gptkb:nucleus
gptkbp:organism gptkb:Drosophila_melanogaster
gptkbp:orthologIn mammalian PRC2
gptkbp:regulates Hox gene expression
gptkbp:requires maintenance of repressed chromatin state
gptkbp:bfsParent gptkb:Polycomb_Repressive_Complex_2
gptkbp:bfsLayer 8