Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
nonsteroidal anti-inflammatory drug |
| gptkbp:activeIngredient |
gptkb:diclofenac
|
| gptkbp:ATCCode |
gptkb:M01AB05
|
| gptkbp:availableOn |
gptkb:tablet
injection gel suppository |
| gptkbp:brand |
gptkb:Voltaren
gptkb:Cataflam gptkb:Zipsor gptkb:Zorvolex |
| gptkbp:CASNumber |
15307-79-6
|
| gptkbp:contraindication |
asthma
peptic ulcer hypersensitivity to NSAIDs severe heart failure |
| gptkbp:discoveredBy |
gptkb:Ciba-Geigy
|
| gptkbp:drugClass |
gptkb:NSAID
|
| gptkbp:eliminationHalfLife |
1-2 hours
|
| gptkbp:excretion |
urine
bile |
| gptkbp:hasMolecularFormula |
C14H10Cl2NNaO2
|
| https://www.w3.org/2000/01/rdf-schema#label |
Diclofenac Sodium
|
| gptkbp:introducedIn |
1973
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
COX inhibitor
prostaglandin synthesis inhibitor |
| gptkbp:metabolism |
liver
|
| gptkbp:pregnancyCategory |
D (in third trimester)
|
| gptkbp:riskFactor |
gastrointestinal bleeding
renal impairment cardiovascular events |
| gptkbp:routeOfAdministration |
oral
topical intramuscular rectal |
| gptkbp:sideEffect |
nausea
dizziness headache rash elevated liver enzymes gastrointestinal upset |
| gptkbp:usedFor |
pain relief
inflammation reduction treatment of arthritis treatment of ankylosing spondylitis treatment of dysmenorrhea treatment of migraines |
| gptkbp:bfsParent |
gptkb:Panaflex_Gold
gptkb:Panaflex_Platinum |
| gptkbp:bfsLayer |
7
|