Ddit3

GPTKB entity

Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alias gptkb:C/EBP_zeta
gptkbp:alsoKnownAs gptkb:CHOP
gptkb:GADD153
C/EBP homologous protein
gptkbp:associatedWith gptkb:cancer
neurodegenerative diseases
metabolic diseases
gptkbp:encodes gptkb:DNA_damage-inducible_transcript_3_protein
gptkbp:Entrez_Gene_ID 13198
ENSMUSG00000023929
gptkbp:expressedIn various tissues
gptkbp:firstDescribed 1993
gptkbp:function transcription factor
https://www.w3.org/2000/01/rdf-schema#label Ddit3
gptkbp:involvedIn apoptosis
cellular stress response
endoplasmic reticulum stress response
gptkbp:length 169 amino acids
gptkbp:locatedOnChromosome mouse chromosome 10
gptkbp:memberOf gptkb:C/EBP_family
gptkbp:organism gptkb:Mus_musculus
gptkbp:orthologIn human DDIT3
gptkbp:proteinFamily basic leucine zipper (bZIP) domain
gptkbp:regulates gene expression
cell cycle arrest
apoptotic pathways
gptkbp:UniProtID P35638
gptkbp:upregulatedBy DNA damage
ER stress
gptkbp:bfsParent gptkb:DDIT3
gptkbp:bfsLayer 7