DNase II

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:alternativeName acid DNase
acid deoxyribonuclease
gptkbp:associatedWith autoimmune disorders (if mutated)
gptkbp:CASNumber 9025-39-2
gptkbp:cofactor_requirement does not require divalent cations
gptkbp:EC_number 3.1.22.1
gptkbp:foundIn animals
plants
some protozoa
gptkbp:function deoxyribonuclease activity
hydrolyzes DNA under acidic conditions
gptkbp:gene DNASE2
https://www.w3.org/2000/01/rdf-schema#label DNase II
gptkbp:location gptkb:lysosome
gptkbp:optimum_pH acidic
gptkbp:product oligonucleotides with 3'-phosphates
gptkbp:relatedTo apoptosis
innate immunity
DNA degradation
gptkbp:substrate gptkb:gene
gptkbp:bfsParent gptkb:DNase
gptkbp:bfsLayer 7