Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:enzyme
|
gptkbp:alternativeName |
acid DNase
acid deoxyribonuclease |
gptkbp:associatedWith |
autoimmune disorders (if mutated)
|
gptkbp:CASNumber |
9025-39-2
|
gptkbp:cofactor_requirement |
does not require divalent cations
|
gptkbp:EC_number |
3.1.22.1
|
gptkbp:foundIn |
animals
plants some protozoa |
gptkbp:function |
deoxyribonuclease activity
hydrolyzes DNA under acidic conditions |
gptkbp:gene |
DNASE2
|
https://www.w3.org/2000/01/rdf-schema#label |
DNase II
|
gptkbp:location |
gptkb:lysosome
|
gptkbp:optimum_pH |
acidic
|
gptkbp:product |
oligonucleotides with 3'-phosphates
|
gptkbp:relatedTo |
apoptosis
innate immunity DNA degradation |
gptkbp:substrate |
gptkb:gene
|
gptkbp:bfsParent |
gptkb:DNase
|
gptkbp:bfsLayer |
7
|