Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
LIG4
DNA ligase IV, ATP-dependent |
| gptkbp:associatedWith |
immunodeficiency
microcephaly radiosensitivity |
| gptkbp:biologicalProcess |
gptkb:V(D)J_recombination
double-strand break repair ATP-dependent DNA ligase activity |
| gptkbp:cellularComponent |
gptkb:nucleus
|
| gptkbp:EC_number |
6.5.1.1
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
gptkb:non-homologous_end_joining
DNA repair |
| gptkbp:gene |
LIG4
|
| https://www.w3.org/2000/01/rdf-schema#label |
DNA ligase IV
|
| gptkbp:interactsWith |
XRCC4
XLF (Cernunnos) |
| gptkbp:locatedOnChromosome |
chromosome 13q33-q34
|
| gptkbp:mutationAssociatedWith |
LIG4 syndrome
|
| gptkbp:OMIM |
601837
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:requires |
DNA double-strand break repair
lymphocyte development |
| gptkbp:UniProtID |
P49917
|
| gptkbp:bfsParent |
gptkb:CHEBI:15765
|
| gptkbp:bfsLayer |
7
|