DNA-dependent DNA polymerase
GPTKB entity
Statements (57)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:Biology
|
| gptkbp:components |
replication fork
DNA polymerase complex |
| gptkbp:function |
synthesizes DNA molecules from deoxyribonucleotides
|
| gptkbp:has_role |
DNA repair
proofreading |
| gptkbp:has_type |
alpha polymerase
beta polymerase delta polymerase epsilon polymerase gamma polymerase |
| https://www.w3.org/2000/01/rdf-schema#label |
DNA-dependent DNA polymerase
|
| gptkbp:initiated_by |
gptkb:azidothymidine_(AZT)
gptkb:acyclovir gptkb:didanosine gptkb:lamivudine gptkb:tenofovir |
| gptkbp:involved_in |
DNA replication
|
| gptkbp:is_associated_with |
aging
genetic disorders cancer progression |
| gptkbp:is_essential_for |
cell division
|
| gptkbp:is_found_in |
gptkb:Atom
eukaryotes mitochondria prokaryotes |
| gptkbp:is_involved_in |
DNA damage response
chromatin remodeling immune response cellular response to stress chromosomal stability cellular aging cellular differentiation gene expression regulation genetic recombination lagging strand synthesis nucleotide excision repair mutagenesis telomere maintenance Okazaki fragment processing base excision repair leading strand synthesis mismatch repair translesion synthesis RNA primer removal |
| gptkbp:is_regulated_by |
cell cycle
|
| gptkbp:is_studied_in |
gptkb:Genetics
molecular biology biochemistry |
| gptkbp:requires |
magnesium ions
template DNA d NTPs (deoxynucleotide triphosphates) |
| gptkbp:targets |
chemotherapy drugs
antiviral drugs |
| gptkbp:was_a_catalyst_for |
phosphodiester bond formation
|
| gptkbp:bfsParent |
gptkb:RNA_Polymerase
|
| gptkbp:bfsLayer |
4
|