DNA-dependent DNA polymerase
GPTKB entity
Statements (57)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:physicist
|
| gptkbp:bfsLayer |
2
|
| gptkbp:bfsParent |
gptkb:physicist
|
| gptkbp:established |
gptkb:azidothymidine_(AZT)
gptkb:acyclovir gptkb:didanosine gptkb:lamivudine gptkb:tenofovir |
| gptkbp:function |
synthesizes DNA molecules from deoxyribonucleotides
|
| gptkbp:game_components |
replication fork
DNA polymerase complex |
| gptkbp:has_role |
DNA repair
proofreading |
| gptkbp:has_style |
alpha polymerase
beta polymerase delta polymerase epsilon polymerase gamma polymerase |
| https://www.w3.org/2000/01/rdf-schema#label |
DNA-dependent DNA polymerase
|
| gptkbp:is_associated_with |
aging
genetic disorders cancer progression |
| gptkbp:is_essential_for |
cell division
|
| gptkbp:is_found_in |
gptkb:physicist
eukaryotes mitochondria prokaryotes |
| gptkbp:is_involved_in |
DNA replication
DNA damage response chromatin remodeling immune response cellular response to stress chromosomal stability cellular aging cellular differentiation gene expression regulation genetic recombination lagging strand synthesis nucleotide excision repair mutagenesis telomere maintenance Okazaki fragment processing base excision repair leading strand synthesis mismatch repair translesion synthesis RNA primer removal |
| gptkbp:is_studied_in |
gptkb:physicist
molecular biology biochemistry |
| gptkbp:regulates |
cell cycle
|
| gptkbp:requires |
magnesium ions
template DNA d NT Ps (deoxynucleotide triphosphates) |
| gptkbp:targets |
chemotherapy drugs
antiviral drugs |
| gptkbp:was_a_catalyst_for |
phosphodiester bond formation
|