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gptkbp:instanceOf
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gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:DOPA_decarboxylase
gptkb:AADC
5-HTP decarboxylase
|
|
gptkbp:associatedWith
|
gptkb:Parkinson's_disease
neurotransmitter metabolism
aromatic L-amino acid decarboxylase deficiency
|
|
gptkbp:biologicalProcess
|
aromatic-L-amino-acid decarboxylase activity
dopamine biosynthetic process
serotonin biosynthetic process
|
|
gptkbp:discoveredBy
|
1960s
|
|
gptkbp:encodes
|
aromatic L-amino acid decarboxylase
|
|
gptkbp:Entrez_Gene_ID
|
1644
|
|
gptkbp:enzymeCommissionNumber
|
4.1.1.28
|
|
gptkbp:expressedIn
|
gptkb:kidney
brain
liver
pancreas
|
|
gptkbp:fullName
|
Dopa decarboxylase gene
|
|
gptkbp:function
|
catalyzes decarboxylation of 5-HTP to serotonin
catalyzes decarboxylation of L-DOPA to dopamine
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:2706
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
DDC gene
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_7
gptkb:7p12.2
|
|
gptkbp:mutationAssociatedWith
|
aromatic L-amino acid decarboxylase deficiency
|
|
gptkbp:OMIM
|
107930
|
|
gptkbp:orthologInMouse
|
Ddc
|
|
gptkbp:product
|
aromatic L-amino acid decarboxylase
|
|
gptkbp:UniProtID
|
P20711
|
|
gptkbp:bfsParent
|
gptkb:DOPA_decarboxylase
|
|
gptkbp:bfsLayer
|
7
|