Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alsoKnownAs |
gptkb:DOPA_decarboxylase
|
| gptkbp:associatedWith |
dopamine biosynthesis
serotonin biosynthesis |
| gptkbp:cofactor |
gptkb:pyridoxal_phosphate
|
| gptkbp:deficiencyCauses |
gptkb:AADC_deficiency
|
| gptkbp:EC_number |
4.1.1.28
|
| gptkbp:expressedIn |
neurons
peripheral tissues |
| gptkbp:foundIn |
gptkb:kidney
brain liver |
| gptkbp:fullName |
aromatic L-amino acid decarboxylase
|
| gptkbp:function |
catalyzes decarboxylation of 5-HTP to serotonin
catalyzes decarboxylation of L-DOPA to dopamine |
| gptkbp:gene |
gptkb:DDC
|
| https://www.w3.org/2000/01/rdf-schema#label |
AADC
|
| gptkbp:inhibitedBy |
benserazide
carbidopa |
| gptkbp:locatedOnChromosome |
chromosome 7p12.2
|
| gptkbp:location |
gptkb:cytoplasm
|
| gptkbp:molecularWeight |
~54 kDa
|
| gptkbp:OMIM |
107930
|
| gptkbp:structure |
homodimer
|
| gptkbp:UniProtID |
P20711
|
| gptkbp:usedIn |
Parkinson's disease treatment
|
| gptkbp:bfsParent |
gptkb:Army_Air_Defence_College
gptkb:DOPA_decarboxylase |
| gptkbp:bfsLayer |
7
|