|
gptkbp:instanceOf
|
gptkb:drug
|
|
gptkbp:ATCCode
|
N02BE01
|
|
gptkbp:bioavailability
|
80–100%
|
|
gptkbp:boilingPoint
|
140°C (decomposes)
|
|
gptkbp:CASNumber
|
50-78-2
|
|
gptkbp:color
|
white
|
|
gptkbp:contraindication
|
asthma
peptic ulcer
children with viral infections
|
|
gptkbp:discoveredBy
|
gptkb:Felix_Hoffmann
|
|
gptkbp:discoveredIn
|
1897
|
|
gptkbp:drugClass
|
gptkb:NSAID
gptkb:anticoagulant
|
|
gptkbp:eliminatedIn
|
renal
|
|
gptkbp:eliminationHalfLife
|
2–3 hours
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:flavor
|
bitter
|
|
gptkbp:hasChEMBL
|
CHEMBL25
|
|
gptkbp:hasInChIKey
|
BSYNRYMUTXBXSQ-UHFFFAOYSA-N
|
|
gptkbp:hasMolecularFormula
|
C9H8O4
|
|
gptkbp:haspKa
|
3.5
|
|
gptkbp:hasPregnancyCategoryAU
|
C
|
|
gptkbp:hasPregnancyCategoryUS
|
N
|
|
gptkbp:hasSMILES
|
CC(=O)Oc1ccccc1C(=O)O
|
|
gptkbp:hasUNII
|
362O9ITL9D
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
D00521
|
|
gptkbp:IUPACName
|
2-acetoxybenzoic acid
|
|
gptkbp:legalStatus
|
gptkb:OTC
|
|
gptkbp:marketedAs
|
gptkb:Bayer
|
|
gptkbp:mechanismOfAction
|
COX inhibitor
|
|
gptkbp:meltingPoint
|
135°C
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
180.16 g/mol
|
|
gptkbp:pregnancyCategory
|
D (third trimester)
|
|
gptkbp:proteinBinding
|
80–90%
|
|
gptkbp:PubChem_CID
|
2244
15365
DB00316
|
|
gptkbp:routeOfAdministration
|
oral
rectal
|
|
gptkbp:sideEffect
|
gastrointestinal bleeding
allergic reaction
ulcer
|
|
gptkbp:solubility
|
3 g/L (20°C)
|
|
gptkbp:synonym
|
gptkb:acetylsalicylic_acid
gptkb:aspirin
|
|
gptkbp:usedFor
|
fever
pain
inflammation
antiplatelet
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
true
|
|
gptkbp:bfsParent
|
gptkb:Gemcitabine
|
|
gptkbp:bfsLayer
|
7
|