|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
Cyp2e
Cyp2e-1
|
|
gptkbp:associatedWith
|
acetaminophen toxicity
alcohol-induced liver injury
|
|
gptkbp:biologicalProcess
|
oxidoreductase activity
|
|
gptkbp:cellularComponent
|
endoplasmic reticulum membrane
|
|
gptkbp:encodes
|
cytochrome P450 2E1
|
|
gptkbp:Entrez_Gene_ID
|
13110
|
|
gptkbp:enzyme
|
monooxygenase
|
|
gptkbp:enzymeCommissionNumber
|
gptkb:EC_1.14.14.1
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:kidney
brain
liver
|
|
gptkbp:function
|
drug metabolism
xenobiotic metabolism
|
|
gptkbp:gene
|
gptkb:Cyp2e1
|
|
gptkbp:geneType
|
protein-coding
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Cyp2e1
|
|
gptkbp:inducedBy
|
gptkb:acetone
ethanol
|
|
gptkbp:length
|
493
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_7_(mouse)
|
|
gptkbp:organism
|
gptkb:Mus_musculus
|
|
gptkbp:orthologIn
|
CYP2E1 (human)
CYP2E1 (rat)
|
|
gptkbp:pathway
|
drug metabolism - cytochrome P450
metabolism of xenobiotics by cytochrome P450
|
|
gptkbp:proteinFamily
|
gptkb:cytochrome_P450
|
|
gptkbp:regulates
|
induced by fasting
inhibited by diallyl sulfide
inhibited by disulfiram
|
|
gptkbp:sequence_location
|
mouse genome build GRCm39
|
|
gptkbp:substrate
|
gptkb:chlorzoxazone
ethanol
acetaminophen
aniline
|
|
gptkbp:UniProtID
|
P10632
|
|
gptkbp:bfsParent
|
gptkb:chromosome_7_(mouse)
|
|
gptkbp:bfsLayer
|
7
|