Statements (22)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:abbreviation |
gptkb:CRM197
|
gptkbp:alternativeName |
gptkb:CRM197
|
gptkbp:derivedFrom |
gptkb:Corynebacterium_diphtheriae
|
gptkbp:discoveredIn |
1970s
|
gptkbp:function |
non-toxic mutant of diphtheria toxin
|
https://www.w3.org/2000/01/rdf-schema#label |
Cross-Reacting Material 197
|
gptkbp:molecularWeight |
58 kDa
|
gptkbp:mutationAssociatedWith |
gptkb:Gly52Glu
|
gptkbp:producedBy |
recombinant expression
|
gptkbp:relatedTo |
gptkb:diphtheria_toxin
|
gptkbp:structure |
single polypeptide chain
|
gptkbp:toxicity |
non-toxic
|
gptkbp:usedAs |
carrier protein in conjugate vaccines
|
gptkbp:usedFor |
immunogenicity enhancement
|
gptkbp:usedIn |
gptkb:meningococcal_conjugate_vaccines
pneumococcal conjugate vaccines conjugate vaccine production Haemophilus influenzae type b (Hib) conjugate vaccines |
gptkbp:bfsParent |
gptkb:CRM197_protein_carrier
gptkb:CRM197_protein |
gptkbp:bfsLayer |
7
|