Cross-Reacting Material 197

GPTKB entity

Statements (22)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:abbreviation gptkb:CRM197
gptkbp:alternativeName gptkb:CRM197
gptkbp:derivedFrom gptkb:Corynebacterium_diphtheriae
gptkbp:discoveredIn 1970s
gptkbp:function non-toxic mutant of diphtheria toxin
https://www.w3.org/2000/01/rdf-schema#label Cross-Reacting Material 197
gptkbp:molecularWeight 58 kDa
gptkbp:mutationAssociatedWith gptkb:Gly52Glu
gptkbp:producedBy recombinant expression
gptkbp:relatedTo gptkb:diphtheria_toxin
gptkbp:structure single polypeptide chain
gptkbp:toxicity non-toxic
gptkbp:usedAs carrier protein in conjugate vaccines
gptkbp:usedFor immunogenicity enhancement
gptkbp:usedIn gptkb:meningococcal_conjugate_vaccines
pneumococcal conjugate vaccines
conjugate vaccine production
Haemophilus influenzae type b (Hib) conjugate vaccines
gptkbp:bfsParent gptkb:CRM197_protein_carrier
gptkb:CRM197_protein
gptkbp:bfsLayer 7