CRM197

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:protein
diphtheria toxin mutant
gptkbp:CASNumber gptkb:11042-64-1
gptkbp:distinctFrom diphtheria toxin (single amino acid substitution)
gptkbp:function non-toxic mutant of diphtheria toxin
https://www.w3.org/2000/01/rdf-schema#label CRM197
gptkbp:molecularWeight 58 kDa
gptkbp:mutationAssociatedWith gptkb:Gly52Glu
gptkbp:origin gptkb:Corynebacterium_diphtheriae
gptkbp:producedBy recombinant expression
gptkbp:structure single polypeptide chain
gptkbp:UNII Q1J8A8V977
gptkbp:usedAs amino acid transporter
gptkbp:usedFor vaccine development
immunogenicity enhancement
protein conjugation
gptkbp:usedIn gptkb:Haemophilus_influenzae_type_b_(Hib)_conjugate_vaccine
gptkb:meningococcal_conjugate_vaccine
vaccine
research applications
conjugate vaccines
gptkbp:bfsParent gptkb:Prevnar
gptkbp:bfsLayer 5