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gptkbp:instanceOf
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gptkb:enzyme
|
|
gptkbp:alternativeName
|
gptkb:CK
gptkb:CPK
gptkb:creatine_phosphokinase
|
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gptkbp:biologicalProcess
|
ATP:creatine N-phosphotransferase activity
|
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gptkbp:CASNumber
|
9001-15-4
|
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gptkbp:catalyzes
|
transfer of phosphate group from ATP to creatine
|
|
gptkbp:discoveredBy
|
1927
|
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gptkbp:EC_number
|
2.7.3.2
|
|
gptkbp:elevatedIn
|
myocardial infarction
muscular dystrophy
rhabdomyolysis
strenuous exercise
|
|
gptkbp:encodedBy
|
gptkb:CKB_gene
gptkb:CKM_gene
gptkb:CKMT1_gene
gptkb:CKMT2_gene
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gptkbp:foundIn
|
gptkb:skeletal_muscle
brain tissue
heart tissue
|
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gptkbp:gene
|
gptkb:CK
|
|
gptkbp:GO_term
|
gptkb:GO:0004111
|
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gptkbp:hasBiomarker
|
myocardial infarction
muscle damage
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Creatine kinase
|
|
gptkbp:inhibitedBy
|
sulfonamides
guanidine derivatives
|
|
gptkbp:involves
|
energy metabolism
phosphocreatine system
|
|
gptkbp:measures
|
blood tests
|
|
gptkbp:presentIn
|
mitochondria
cytosol
|
|
gptkbp:product
|
gptkb:ADP
gptkb:phosphocreatine
|
|
gptkbp:significance
|
diagnosis of heart attack
diagnosis of muscle diseases
|
|
gptkbp:structure
|
dimer
|
|
gptkbp:substrate
|
gptkb:ATP
gptkb:creatine
|
|
gptkbp:subunit
|
gptkb:CK-BB
gptkb:CK-MM
gptkb:CK-MB
|
|
gptkbp:UniProtID
|
gptkb:P12277_(CK-BB)
gptkb:P12277_(CK-MB)
P06732 (CK-MM)
|
|
gptkbp:used_in
|
cardiology
neurology
sports medicine
|
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gptkbp:bfsParent
|
gptkb:CK
|
|
gptkbp:bfsLayer
|
6
|