Statements (64)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
enzyme
|
| gptkbp:associated_with |
cardiomyopathy and other heart diseases
rhabdomyolysis, muscular dystrophy, and stroke |
| gptkbp:associatedWith |
biochemistry
sports medicine exercise physiology muscle damage myocardial infarction clinical pathology |
| gptkbp:clinicalTrials |
assessing effectiveness of therapies
diagnosing heart attacks evaluating kidney function guiding treatment for muscle disorders marker for acute kidney injury marker for myocardial injury marker for rhabdomyolysis monitoring muscle diseases monitoring recovery from heart surgery used as a biomarker for myocardial infarction |
| gptkbp:discipline |
can be inhibited by certain drugs and conditions
|
| gptkbp:elevation |
heart attack
certain medications strenuous exercise can indicate muscle damage or stress muscle injury |
| gptkbp:energyEfficiency |
important_for_ATP_regeneration_in_muscle_cells
|
| gptkbp:established |
gptkb:John_E._Walker
Hugo_Theorell_in_1954 |
| gptkbp:firstAwarded |
skeletal muscle
|
| gptkbp:fullName |
gptkb:Creatine_Phosphokinase
|
| gptkbp:function |
catalyzes the conversion of creatine to phosphocreatine
catalyzes_the_conversion_of_creatine_and_ATP_to_creatine_phosphate_and_ADP |
| gptkbp:geneticDiversity |
can affect enzyme levels and activity
|
| gptkbp:hasType |
CK-MB
CK-MM CK-BB |
| https://www.w3.org/2000/01/rdf-schema#label |
CPK
|
| gptkbp:influencedBy |
age
diet physical activity gender |
| gptkbp:involvedIn |
cellular respiration
energy transfer muscle contraction |
| gptkbp:isActiveIn |
adenosine_triphosphate
|
| gptkbp:isOftenUsedIn |
CK-MB predominates in heart muscle
CK-MM predominates in skeletal muscle CK-BB_predominates_in_brain includes_CPK-MM,_CPK-MB,_and_CPK-BB |
| gptkbp:locatedIn |
brain
muscle tissue |
| gptkbp:location |
found in heart, brain, and skeletal muscle
|
| gptkbp:measures |
measured_in_units_per_liter_(U/L)
|
| gptkbp:priceRange |
20 to 200 U/L
|
| gptkbp:range |
typically 10 to 120 micrograms per liter in blood
|
| gptkbp:relatedTo |
energy metabolism
diagnostic tests laboratory medicine cardiac biomarkers creatine metabolism phosphocreatine synthesis ATP_production |
| gptkbp:technique |
measured through blood tests
|
| gptkbp:visitedBy |
blood tests
|