Complex V

GPTKB entity

Statements (51)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:activity rotary catalysis
gptkbp:alsoKnownAs gptkb:ATP_synthase
gptkbp:ATPProductionRate up to 100 ATP/sec per enzyme
gptkbp:catalyticSite gptkb:F1_sector
gptkbp:component oxidative phosphorylation
electron transport chain
gptkbp:discoveredBy gptkb:Paul_Boyer
gptkb:John_E._Walker
gptkbp:EC_number 7.1.2.2
gptkbp:foundIn gptkb:Bacteria
eukaryotes
gptkbp:function synthesizes ATP from ADP and inorganic phosphate
gptkbp:gene gptkb:ATP5F1D
gptkb:ATP5F1E
gptkb:ATP5F1A
gptkb:ATP5F1B
gptkb:ATP5F1C
gptkb:ATP5MC1
gptkb:ATP5MC2
gptkb:ATP5MC3
gptkb:ATP5ME
gptkb:ATP5MF
gptkb:ATP5MG
gptkb:ATP5PB
gptkb:ATP5PD
gptkb:ATP5PF
https://www.w3.org/2000/01/rdf-schema#label Complex V
gptkbp:inhibitedBy gptkb:venturicidin
gptkb:oligomycin
dicyclohexylcarbodiimide (DCCD)
gptkbp:locatedIn inner mitochondrial membrane
gptkbp:molecularWeight ~600 kDa
gptkbp:mutationAssociatedWith mitochondrial diseases
gptkbp:NobelPrizeYear 1997 Chemistry
gptkbp:notableDriver proton gradient
gptkbp:orthologIn A-type ATP synthase in archaea
CF1CF0-ATP synthase in chloroplasts
gptkbp:powerSource proton-motive force to chemical energy
gptkbp:presentIn gptkb:bacterial_plasma_membrane
chloroplasts (as CF1CF0-ATP synthase)
gptkbp:protonChannel Fo sector
gptkbp:requires cellular respiration
aerobic metabolism
gptkbp:rotationPeriod gamma subunit
gptkbp:structure multi-subunit protein complex
gptkbp:subunit gptkb:F1_sector
Fo sector
gptkbp:subunitCount 16 (in mammals)
gptkbp:bfsParent gptkb:ATP_synthase
gptkbp:bfsLayer 7