|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:alternativeName
|
gptkb:Complex_V
gptkb:F1Fo-ATPase
|
|
gptkbp:associatedWith
|
mitochondrial disorders
|
|
gptkbp:ATPProductionRate
|
up to 100 ATP/sec per enzyme
|
|
gptkbp:catalyzes
|
ADP + Pi → ATP + H2O
|
|
gptkbp:component
|
oxidative phosphorylation
photophosphorylation
|
|
gptkbp:discoveredBy
|
gptkb:Paul_Boyer
gptkb:John_E._Walker
|
|
gptkbp:EC_number
|
7.1.2.2
|
|
gptkbp:foundIn
|
gptkb:bacterial_plasma_membrane
gptkb:chloroplast_thylakoid_membrane
mitochondrial inner membrane
|
|
gptkbp:function
|
synthesizes ATP from ADP and inorganic phosphate
|
|
gptkbp:gene
|
gptkb:MT-ATP6
gptkb:ATP5F1A
gptkb:ATP5F1B
gptkb:ATP5F1C
gptkb:ATP5MC1
gptkb:ATP5MC2
gptkb:ATP5MC3
gptkb:ATP5ME
gptkb:ATP5MF
gptkb:ATP5MG
gptkb:ATP5PB
gptkb:ATP5PD
gptkb:ATP5PF
gptkb:MT-ATP8
|
|
gptkbp:GO_term
|
gptkb:GO:0015986
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ATP synthase
|
|
gptkbp:inhibitedBy
|
gptkb:DCCD
gptkb:oligomycin
|
|
gptkbp:mechanismOfAction
|
rotary catalysis
|
|
gptkbp:molecularWeight
|
~600 kDa (mammalian)
|
|
gptkbp:NobelPrizeYear
|
gptkb:1997_Nobel_Prize_in_Chemistry
|
|
gptkbp:notableDriver
|
proton gradient
|
|
gptkbp:OMIM
|
516060
|
|
gptkbp:PDB
|
gptkb:5FIL
gptkb:6CP6
|
|
gptkbp:powerSource
|
proton-motive force
|
|
gptkbp:presentIn
|
all domains of life
|
|
gptkbp:protonTranslocation
|
Fo sector translocates protons
|
|
gptkbp:relatedTo
|
chemiosmosis
|
|
gptkbp:requires
|
cellular energy production
|
|
gptkbp:rotationPeriod
|
gamma subunit rotates during catalysis
|
|
gptkbp:structure
|
multi-subunit protein complex
|
|
gptkbp:subunit
|
gptkb:F1_sector
Fo sector
|
|
gptkbp:UniProtID
|
gptkb:P06576
|
|
gptkbp:bfsParent
|
gptkb:Mitochondrion
gptkb:Enzymes
gptkb:CHEBI:17716
gptkb:Chloroplast
gptkb:CHEBI:17336
|
|
gptkbp:bfsLayer
|
6
|