Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:CD35
gptkb:CR1 |
| gptkbp:associatedWith |
gptkb:Alzheimer's_disease
gptkb:systemic_lupus_erythematosus malaria susceptibility |
| gptkbp:binds |
gptkb:C4b
gptkb:C3b |
| gptkbp:encodedBy |
gptkb:CR1_gene
|
| gptkbp:expressedIn |
gptkb:leukocytes
gptkb:B_cells erythrocytes monocytes some dendritic cells |
| gptkbp:foundIn |
humans
other mammals |
| gptkbp:function |
clearance of immune complexes
regulation of complement activation |
| https://www.w3.org/2000/01/rdf-schema#label |
Complement receptor type 1
|
| gptkbp:locatedOn |
chromosome 1 (human)
|
| gptkbp:molecularWeight |
~200 kDa
|
| gptkbp:OMIM |
120620
|
| gptkbp:role |
immune response
removal of opsonized particles |
| gptkbp:transmembraneDomains |
true
|
| gptkbp:UniProtID |
P17927
|
| gptkbp:bfsParent |
gptkb:CR1
|
| gptkbp:bfsLayer |
7
|