Cluster of Differentiation 4
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
cell surface receptor |
| gptkbp:abbreviation |
gptkb:CD4
|
| gptkbp:alternativeName |
gptkb:T4_antigen
|
| gptkbp:antigen |
yes
|
| gptkbp:discoveredIn |
1980s
|
| gptkbp:encodedBy |
gptkb:CD4_gene
|
| gptkbp:expressedIn |
immune system
|
| gptkbp:foundIn |
dendritic cells
macrophages monocytes T helper cells |
| gptkbp:function |
binds to MHC class II molecules
co-receptor for T cell receptor |
| gptkbp:HGNC_ID |
HGNC:1678
|
| https://www.w3.org/2000/01/rdf-schema#label |
Cluster of Differentiation 4
|
| gptkbp:location |
gptkb:chromosome_12
|
| gptkbp:molecularWeight |
55 kDa
|
| gptkbp:OMIM |
186940
|
| gptkbp:role |
immune response
HIV infection progression |
| gptkbp:structure |
single-chain transmembrane glycoprotein
|
| gptkbp:target |
gptkb:HIV
|
| gptkbp:UniProtID |
P01730
|
| gptkbp:usedAs |
immunological marker
|
| gptkbp:usedIn |
HIV diagnosis
|
| gptkbp:usedToMonitor |
AIDS progression
|
| gptkbp:bfsParent |
gptkb:CD4
|
| gptkbp:bfsLayer |
7
|