Statements (33)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:activity |
ATP-dependent proteolysis
|
gptkbp:associatedWith |
mitochondrial function
protein quality control stress response Perrault syndrome |
gptkbp:discoveredBy |
Maurizi et al.
|
gptkbp:EC_number |
gptkb:3.4.21.92
|
gptkbp:formsComplexWith |
gptkb:ClpA
gptkb:ClpX |
gptkbp:fullName |
Caseinolytic peptidase P
|
gptkbp:function |
gptkb:protease
|
gptkbp:gene |
gptkb:clpP
|
https://www.w3.org/2000/01/rdf-schema#label |
ClpP
|
gptkbp:inhibitedBy |
ADEP antibiotics
|
gptkbp:locatedOnChromosome |
gptkb:chromosome_19_(human)
|
gptkbp:location |
gptkb:cytoplasm
|
gptkbp:molecularWeight |
~21 kDa
|
gptkbp:mutationAssociatedWith |
infertility
hearing loss |
gptkbp:organism |
gptkb:Homo_sapiens
gptkb:Bacteria |
gptkbp:orthologIn |
ClpP (mouse)
ClpP (yeast) |
gptkbp:PDB |
1TYF
|
gptkbp:regulates |
histone modification
allosteric |
gptkbp:structure |
tetradecamer
|
gptkbp:substrate |
regulatory proteins
misfolded proteins |
gptkbp:UniProtID |
P0A6G7
|
gptkbp:bfsParent |
gptkb:Clp_protease
|
gptkbp:bfsLayer |
7
|