|
gptkbp:instanceOf
|
gptkb:antibiotic
cephalosporin
|
|
gptkbp:ATCCode
|
J01DD08
|
|
gptkbp:bioavailability
|
40–50%
|
|
gptkbp:brand
|
Cefspan
Suprax
Zifi
|
|
gptkbp:CASNumber
|
79350-37-1
|
|
gptkbp:chemicalFormula
|
C16H15N5O7S2
|
|
gptkbp:contraindication
|
hypersensitivity to cephalosporins
|
|
gptkbp:discoveredBy
|
gptkb:Fujisawa_Pharmaceutical
|
|
gptkbp:drugClass
|
gptkb:antibiotic
|
|
gptkbp:eliminationHalfLife
|
3–4 hours
|
|
gptkbp:excretion
|
urine
feces
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Cefixime
|
|
gptkbp:interactsWith
|
gptkb:warfarin
gptkb:carbamazepine
oral contraceptives
|
|
gptkbp:introducedIn
|
1989
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits bacterial cell wall synthesis
|
|
gptkbp:metabolism
|
minimal
|
|
gptkbp:molecularWeight
|
453.45 g/mol
|
|
gptkbp:pregnancyCategory
|
B (US)
B1 (Australia)
|
|
gptkbp:prescribes
|
adults
children
|
|
gptkbp:proteinBinding
|
65%
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
nausea
diarrhea
abdominal pain
rash
allergic reactions
|
|
gptkbp:synonym
|
(6R,7R)-7-[2-(2-amino-1,3-thiazol-4-yl)-2-(carboxymethoxyimino)acetamido]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
|
|
gptkbp:usedFor
|
bronchitis
tonsillitis
urinary tract infections
gonorrhea
bacterial infections
otitis media
pharyngitis
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
true
|
|
gptkbp:bfsParent
|
gptkb:Zentiva
|
|
gptkbp:bfsLayer
|
7
|