Casein kinase II subunit alpha

URI: https://gptkb.org/entity/Casein_kinase_II_subunit_alpha
GPTKB entity
Statements (45)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName CK2 alpha
CKII alpha
Casein kinase II catalytic subunit alpha
gptkbp:associatedWith gptkb:cancer
apoptosis
cell proliferation
signal transduction
cell growth
transcription regulation
Okur-Chung neurodevelopmental syndrome
gptkbp:component gptkb:nucleus
gptkb:cytoplasm
casein kinase II holoenzyme
gptkbp:EC_number 2.7.11.1
gptkbp:encodedBy CSNK2A1 gene
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function serine/threonine-protein kinase activity
protein serine/threonine kinase activity
gptkbp:GOProcess cell cycle
regulation of transcription, DNA-templated
gptkbp:interactsWith casein kinase II subunit beta
numerous cellular proteins
gptkbp:involvedIn phosphorylation
gptkbp:locatedOnChromosome gptkb:20p13
gptkbp:location gptkb:nucleus
gptkb:cytoplasm
gptkbp:molecularWeight ~45 kDa
gptkbp:orthologIn gptkb:Mus_musculus
gptkb:Rattus_norvegicus
gptkbp:PDB 1JWH
3NSZ
gptkbp:phosphorylates gptkb:casein
numerous cellular proteins
gptkbp:postTranslationalModification phosphorylation
acetylation
gptkbp:structure gptkb:monomer
tetramer (in holoenzyme)
gptkbp:UniProtID P68400
gptkbp:bfsParent gptkb:CHEMBL1089572
gptkb:2PNU
gptkb:3CF1
gptkb:3KMD
gptkbp:bfsLayer 8
https://www.w3.org/2000/01/rdf-schema#label Casein kinase II subunit alpha