Statements (47)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:DNA
|
| gptkbp:associated_with |
therapeutic drug monitoring
adverse drug reactions pharmacogenomics |
| gptkbp:character_traits |
CYP2 D6*1
CYP2 D6*10 CYP2 D6*17 CYP2 D6*2 CYP2 D6*29 CYP2 D6*3 CYP2 D6*4 CYP2 D6*5 CYP2 D6*6 |
| gptkbp:clinical_trial |
extensive metabolizers
intermediate metabolizers poor metabolizers ultra-rapid metabolizers |
| gptkbp:code |
cytochrome P450 2 D6 protein
|
| gptkbp:fuselage_material |
gptkb:metoprolol
gptkb:tamoxifen codeine desipramine nortriptyline tramadol |
| https://www.w3.org/2000/01/rdf-schema#label |
CYP2 D6
|
| gptkbp:inducers |
gptkb:phenobarbital
gptkb:carbamazepine gptkb:rifampicin |
| gptkbp:influences |
drug response variability
|
| gptkbp:initiated_by |
gptkb:bupropion
gptkb:paroxetine fluoxetine |
| gptkbp:involved_in |
drug metabolism
|
| gptkbp:is_expressed_in |
gptkb:Brain
kidney liver |
| gptkbp:located_in |
human chromosome 22
|
| gptkbp:metabolism |
antidepressants
opioids beta-blockers |
| gptkbp:research_focus |
toxicology
genetic testing personalized medicine drug-drug interactions clinical pharmacology |
| gptkbp:bfsParent |
gptkb:Biology
|
| gptkbp:bfsLayer |
3
|