Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:chemokine_family
|
gptkbp:binds |
CXC chemokine receptors
|
gptkbp:discoveredIn |
1990s
|
gptkbp:example |
gptkb:CXCL1
gptkb:CXCL10 gptkb:CXCL12 gptkb:CXCL8 |
gptkbp:function |
chemotaxis
immune cell recruitment |
https://www.w3.org/2000/01/rdf-schema#label |
CXC chemokines
|
gptkbp:locatedOnChromosome |
gptkb:chromosome_4_(human)
|
gptkbp:nomenclature |
CXCL (CXC ligand)
|
gptkbp:producedBy |
gptkb:leukocytes
endothelial cells |
gptkbp:receptorFamily |
CXCR (CXC receptor)
|
gptkbp:role |
wound healing
angiogenesis inflammation cancer metastasis |
gptkbp:structure |
conserved cysteine residues separated by one amino acid
|
gptkbp:subclassOf |
cytokines
|
gptkbp:bfsParent |
gptkb:CXC_domain
|
gptkbp:bfsLayer |
8
|