CUGBP Elav-like family member 1

URI: https://gptkb.org/entity/CUGBP_Elav-like_family_member_1
GPTKB entity
Statements (42)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:gene
gptkbp:alsoKnownAs gptkb:CELF1
gptkb:CUGBP1
gptkbp:associatedWith gptkb:myotonic_dystrophy
gptkbp:discoveredBy Timothy A. Cooper
gptkbp:domain RNA recognition motif
gptkbp:encodedBy gptkb:CELF1_gene
gptkbp:Entrez_Gene_ID gptkb:ENSG00000149187
10658
gptkbp:expressedIn gptkb:skeletal_muscle
gptkb:testis
brain
heart
liver
gptkbp:firstDescribed 1995
gptkbp:function RNA binding
regulation of mRNA translation
regulation of alternative splicing
regulation of mRNA stability
gptkbp:HGNC_ID HGNC:2452
https://www.w3.org/2000/01/rdf-schema#label CUGBP Elav-like family member 1
gptkbp:interactsWith gptkb:CUGBP2
gptkb:MBNL1
eIF2
PABP
gptkbp:length 489 amino acids
gptkbp:locatedOnChromosome chromosome 11
gptkbp:memberOf gptkb:CELF_protein_family
gptkbp:molecularWeight 53 kDa
gptkbp:OMIM 601074
gptkbp:orthologInMouse gptkb:Celf1
gptkbp:orthologInZebrafish celf1
gptkbp:phosphorylates gptkb:protein_kinase_C
cyclin-dependent kinase 2
gptkbp:regulates alternative splicing of cardiac troponin T
alternative splicing of insulin receptor
gptkbp:subcellularLocation gptkb:nucleus
gptkb:cytoplasm
gptkbp:UniProtID gptkb:Q92879
gptkbp:bfsParent gptkb:CELF1
gptkbp:bfsLayer 8