|
gptkbp:instanceOf
|
gptkb:antibiotic
|
|
gptkbp:alternativeName
|
gptkb:Cefotaxime
|
|
gptkbp:approvedBy
|
gptkb:FDA
1980
|
|
gptkbp:ATCCode
|
J01DD01
|
|
gptkbp:chemicalFormula
|
C16H17N5O7S2
|
|
gptkbp:contraindication
|
hypersensitivity to cephalosporins
|
|
gptkbp:discoveredBy
|
gptkb:Hoechst_AG
|
|
gptkbp:drugClass
|
cephalosporin
|
|
gptkbp:eliminationHalfLife
|
1 hour
|
|
gptkbp:excretion
|
renal
|
|
gptkbp:generation
|
third-generation
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CTX001
|
|
gptkbp:indication
|
gptkb:pneumonia
meningitis
sepsis
urinary tract infection
bacterial endocarditis
gonorrhea
intra-abdominal infections
skin and soft tissue infections
bone and joint infections
gynecological infections
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits cell wall synthesis
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
455.47 g/mol
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:routeOfAdministration
|
intramuscular
intravenous
|
|
gptkbp:sideEffect
|
diarrhea
allergic reaction
rash
|
|
gptkbp:spectrumOfActivity
|
broad-spectrum
|
|
gptkbp:usedFor
|
bacterial infections
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
included
|
|
gptkbp:bfsParent
|
gptkb:CRISPR_Therapeutics
|
|
gptkbp:bfsLayer
|
6
|