Statements (108)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alternativeName |
CTP synthase 1
CTPS CTPSase 1 |
| gptkbp:associatedWith |
gptkb:immunodeficiency_19
|
| gptkbp:biologicalProcess |
ATP binding
nucleotide biosynthetic process CTP synthase activity glutamine amidotransferase activity pyrimidine biosynthetic process |
| gptkbp:encodedBy |
CTPS1 gene
|
| gptkbp:Entrez_Gene_ID |
1503
|
| gptkbp:enzymeCommissionNumber |
EC 6.3.4.2
|
| gptkbp:fullName |
CTP synthase 1
|
| gptkbp:function |
catalyzes the conversion of UTP to CTP
|
| gptkbp:geneType |
protein-coding
|
| gptkbp:HGNC_ID |
HGNC:2511
|
| https://www.w3.org/2000/01/rdf-schema#label |
CTPS1 (human)
|
| gptkbp:location |
gptkb:cytoplasm
gptkb:chromosome_1q23.3 |
| gptkbp:mutationAssociatedWith |
impaired T and B cell proliferation
|
| gptkbp:OMIM |
605574
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
mouse Ctp synthase 1
rat Ctp synthase 1 |
| gptkbp:PDB |
2V4U
2V4V 2V4W 2V4X 2V4Y 2V4Z 2V50 2V51 2V52 2V53 2V54 2V55 2V56 2V57 2V58 2V59 2V5A 2V5B 2V5C 2V5D 2V5E 2V5F 2V5G 2V5H 2V5I 2V5J 2V5K 2V5L 2V5M 2V5N 2V5O 2V5P 2V5Q 2V5R 2V5S 2V5T 2V5U 2V5V 2V5W 2V5X 2V5Y 2V5Z 2V60 2V61 2V62 2V63 2V64 2V65 2V66 2V67 2V68 2V69 2V6A 2V6B 2V6C 2V6D 2V6E 2V6F 2V6G 2V6H 2V6I 2V6J 2V6K 2V6L 2V6M 2V6N 2V6O 2V6P 2V6Q 2V6R 2V6S 2V6T 2V6U 2V6V 2V6W 2V6X 2V6Y 2V6Z |
| gptkbp:requires |
lymphocyte proliferation
|
| gptkbp:UniProtID |
O43543
|
| gptkbp:bfsParent |
gptkb:URA7
|
| gptkbp:bfsLayer |
7
|