Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alsoKnownAs |
gptkb:CD27_ligand
TNFSF7 |
| gptkbp:associatedWith |
autoimmune diseases
lymphomas |
| gptkbp:binds |
gptkb:CD27
|
| gptkbp:encodedBy |
CD70 gene
|
| gptkbp:Entrez_Gene_ID |
970
|
| gptkbp:expressedIn |
dendritic cells
activated T cells activated B cells |
| gptkbp:form |
homotrimer
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
costimulatory molecule in immune response
|
| gptkbp:HGNC_ID |
11916
|
| https://www.w3.org/2000/01/rdf-schema#label |
CD70
|
| gptkbp:involvedIn |
T cell activation
immune regulation B cell activation |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_19q13.4
|
| gptkbp:memberOf |
tumor necrosis factor ligand family
|
| gptkbp:molecularWeight |
~30 kDa
|
| gptkbp:OMIM |
186643
|
| gptkbp:regulates |
apoptosis
lymphocyte proliferation |
| gptkbp:structure |
type II transmembrane protein
|
| gptkbp:target |
immunotherapy
|
| gptkbp:UniProtID |
P32970
|
| gptkbp:bfsParent |
gptkb:CD27
gptkb:TNFRSF gptkb:CD27_ligand gptkb:TNF_ligand_superfamily |
| gptkbp:bfsLayer |
8
|