Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
cell surface receptor |
| gptkbp:alternativeName |
gptkb:OKT4
gptkb:T4_antigen leu-3 |
| gptkbp:binds |
gptkb:MHC_class_II_molecules
|
| gptkbp:discoveredIn |
1980s
|
| gptkbp:encodedBy |
gptkb:CD4_gene
|
| gptkbp:expressedIn |
humans
mammals |
| gptkbp:foundIn |
dendritic cells
macrophages monocytes T helper cells |
| gptkbp:function |
immune response regulation
co-receptor for T cell receptor |
| https://www.w3.org/2000/01/rdf-schema#label |
CD4 molecule
|
| gptkbp:importantFor |
immunology
transplantation immunology HIV/AIDS diagnosis |
| gptkbp:interactsWith |
p56lck (tyrosine kinase)
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_12_(human)
|
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:molecularWeight |
~55 kDa
|
| gptkbp:structure |
single-chain glycoprotein
|
| gptkbp:target |
gptkb:HIV
|
| gptkbp:usedAs |
marker for T helper cells
|
| gptkbp:usedFor |
assess immune function
classify lymphocytes monitor HIV progression |
| gptkbp:bfsParent |
gptkb:MHC_class_II_molecules
|
| gptkbp:bfsLayer |
7
|