|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
gptkb:IMD18
gptkb:T3E
CD3EAP
|
|
gptkbp:alternativeName
|
gptkb:CD3-epsilon
gptkb:T3E
gptkb:T-cell_surface_glycoprotein_CD3_epsilon_chain
|
|
gptkbp:associatedWith
|
gptkb:Immunodeficiency_18
gptkb:Severe_combined_immunodeficiency
|
|
gptkbp:component
|
gptkb:T-cell_receptor-CD3_complex
|
|
gptkbp:discoveredBy
|
1980s
|
|
gptkbp:encodes
|
gptkb:T-cell_surface_glycoprotein_CD3_epsilon_chain
|
|
gptkbp:Entrez_Gene_ID
|
916
ENSG00000198851
|
|
gptkbp:expressedIn
|
gptkb:T_cells
|
|
gptkbp:function
|
signal transduction
T-cell activation
|
|
gptkbp:gene
|
gptkb:CD3E
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GO_term
|
GO:0042101 (T cell activation)
GO:0007166 (cell surface receptor signaling pathway)
|
|
gptkbp:hasTranscriptVariant
|
NM_000733.4
|
|
gptkbp:HGNC_ID
|
1675
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CD3E (human)
|
|
gptkbp:interactsWith
|
gptkb:CD3G
gptkb:CD3D
CD247 (CD3Z)
TCR alpha/beta
TCR gamma/delta
|
|
gptkbp:length
|
207
|
|
gptkbp:locatedOnChromosome
|
11
11q23.3
|
|
gptkbp:molecularWeight
|
20-25 kDa
|
|
gptkbp:OMIM
|
186830
|
|
gptkbp:orthologInMouse
|
gptkb:Cd3e
|
|
gptkbp:PDB
|
1XIW
|
|
gptkbp:postTranslationalModification
|
phosphorylation
|
|
gptkbp:proteinFamily
|
gptkb:immunoglobulin_superfamily
|
|
gptkbp:RefSeq
|
gptkb:NM_000733
|
|
gptkbp:subcellularLocation
|
gptkb:plasma_membrane
|
|
gptkbp:UniProtID
|
P07766
|
|
gptkbp:bfsParent
|
gptkb:Cd3e
|
|
gptkbp:bfsLayer
|
8
|