CD166

GPTKB entity

Statements (38)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs ALCAM
gptkbp:associatedWith gptkb:cancer
autoimmune diseases
neurological disorders
gptkbp:cellSurfaceMarker yes
gptkbp:discoveredIn 1990s
gptkbp:encodedBy ALCAM gene
gptkbp:Entrez_Gene_ID 214
gptkbp:expressedIn gptkb:T_cells
cancer cells
endothelial cells
epithelial cells
gptkbp:fullName Activated Leukocyte Cell Adhesion Molecule
gptkbp:function immune response
neuronal development
cell adhesion
gptkbp:gene ALCAM
gptkbp:HGNC_ID 405
https://www.w3.org/2000/01/rdf-schema#label CD166
gptkbp:interactsWith CD6
gptkbp:locatedOnChromosome 3q13.11
gptkbp:memberOf gptkb:immunoglobulin_superfamily
gptkbp:molecularWeight ~105 kDa
gptkbp:OMIM 604603
gptkbp:orthologInMouse Alcam
gptkbp:PDB 3BCL
gptkbp:role cell proliferation
angiogenesis
cell migration
metastasis
tumor progression
gptkbp:structure type I transmembrane glycoprotein
gptkbp:UniProtID Q13740
gptkbp:usedAs cancer stem cell marker
stem cell marker
gptkbp:bfsParent gptkb:immunoglobulin_superfamily
gptkbp:bfsLayer 7