|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:TRiC
chaperonin containing TCP-1
|
|
gptkbp:assistsFoldingOf
|
gptkb:actin
tubulin
|
|
gptkbp:associatedWith
|
gptkb:cancer
neurodegenerative diseases
|
|
gptkbp:ATPaseActivity
|
yes
|
|
gptkbp:component
|
cytosol
chaperonin-containing T-complex
|
|
gptkbp:composedOf
|
eight different subunits
|
|
gptkbp:discoveredIn
|
1990s
|
|
gptkbp:evolutionaryConservation
|
high
|
|
gptkbp:foundIn
|
eukaryotes
|
|
gptkbp:function
|
protein folding
unfolded protein binding
|
|
gptkbp:gene
|
gptkb:CCT
|
|
gptkbp:GOProcess
|
protein folding
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CCT protein
|
|
gptkbp:interactsWith
|
WD40 repeat proteins
cell cycle proteins
phosducin
|
|
gptkbp:involvedIn
|
prevention of protein aggregation
protein homeostasis
|
|
gptkbp:locale
|
gptkb:cytoplasm
|
|
gptkbp:molecularWeight
|
~970 kDa
|
|
gptkbp:numberOfSubunits
|
8
|
|
gptkbp:OMIM
|
600978
|
|
gptkbp:orthologIn
|
GroEL (bacterial chaperonin)
|
|
gptkbp:regulates
|
ATP-dependent
|
|
gptkbp:relatedTo
|
heat shock proteins
|
|
gptkbp:requires
|
cell division
protein quality control
cell viability
cytoskeletal assembly
|
|
gptkbp:structure
|
double-ring complex
|
|
gptkbp:subcellularLocation
|
cytosol
nucleus (minor fraction)
|
|
gptkbp:subunit
|
gptkb:CCT1
gptkb:CCT2
gptkb:CCT3
gptkb:CCT4
gptkb:CCT5
gptkb:CCT6
gptkb:CCT7
gptkb:CCT8
|
|
gptkbp:UniProtID
|
P49368 (CCT1 subunit)
|
|
gptkbp:bfsParent
|
gptkb:CCT_(gene)
|
|
gptkbp:bfsLayer
|
7
|