Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:activeSiteResidue |
histidine
|
| gptkbp:associatedWith |
gptkb:osteopetrosis
renal tubular acidosis |
| gptkbp:catalyzes |
hydration of carbon dioxide
|
| gptkbp:cofactor |
zinc
|
| gptkbp:EC_number |
4.2.1.1
|
| gptkbp:expressedIn |
gptkb:kidney
gptkb:osteoclasts gastrointestinal tract erythrocytes |
| gptkbp:family |
gptkb:carbonic_anhydrase_family
|
| gptkbp:foundIn |
humans
mammals |
| gptkbp:function |
regulation of acid-base balance
CO2 transport |
| gptkbp:gene |
gptkb:CA2
|
| gptkbp:HGNC_ID |
1373
|
| https://www.w3.org/2000/01/rdf-schema#label |
Carbonic anhydrase II
|
| gptkbp:inhibitedBy |
gptkb:acetazolamide
gptkb:brinzolamide gptkb:methazolamide gptkb:dorzolamide |
| gptkbp:locatedIn |
gptkb:cytoplasm
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_8q21.2
|
| gptkbp:molecularWeight |
29 kDa
|
| gptkbp:OMIM |
611492
|
| gptkbp:PDB |
gptkb:1CA2
|
| gptkbp:RefSeq |
NP_000058.1
|
| gptkbp:structure |
monomer
|
| gptkbp:UniProtID |
P00918
|
| gptkbp:bfsParent |
gptkb:1HL5
gptkb:1R42 |
| gptkbp:bfsLayer |
6
|