|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
CAPPA2_HUMAN
CapZ alpha-2
F-actin-capping protein subunit alpha-2
|
|
gptkbp:associatedWith
|
cytoskeleton
|
|
gptkbp:biologicalProcess
|
muscle contraction
actin cytoskeleton organization
actin filament binding
|
|
gptkbp:component
|
capping protein complex
|
|
gptkbp:discoveredBy
|
1990s
|
|
gptkbp:encodes
|
F-actin-capping protein subunit alpha-2
|
|
gptkbp:Entrez_Gene_ID
|
8313
ENSG00000164683
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:skeletal_muscle
gptkb:kidney
brain
heart
liver
various tissues including brain and muscle
|
|
gptkbp:function
|
regulation of actin filament dynamics
|
|
gptkbp:gene
|
gptkb:CAPZA2
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:2322
|
|
gptkbp:interactsWith
|
gptkb:actin
CAPZB
|
|
gptkbp:involves
|
signal transduction
cell motility
cell shape maintenance
|
|
gptkbp:length
|
286
|
|
gptkbp:locatedOnChromosome
|
7q31.2
|
|
gptkbp:molecularWeight
|
32 kDa
|
|
gptkbp:mutationAssociatedWith
|
neurological disorders
|
|
gptkbp:OMIM
|
602349
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse
gptkb:right
gptkb:zebrafish
|
|
gptkbp:proteinFamily
|
F-actin-capping protein alpha subunit family
|
|
gptkbp:RefSeq
|
NM_001206541
NP_001193470
|
|
gptkbp:regulates
|
actin filament growth
actin filament stability
|
|
gptkbp:subcellularLocation
|
gptkb:cytoplasm
cytoskeleton
|
|
gptkbp:UniProtID
|
Q08378
|
|
gptkbp:bfsParent
|
gptkb:chromosome_7q31
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CAPZA2
|