|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
CAMKII subunit delta
CaMKII delta
CaMKII-delta
|
|
gptkbp:alternativeSplicing
|
produces multiple isoforms
|
|
gptkbp:associatedWith
|
gptkb:arrhythmia
heart failure
cardiomyopathy
|
|
gptkbp:biologicalProcess
|
signal transduction
protein kinase activity
regulation of heart contraction
calmodulin binding
learning or memory
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
synapse
|
|
gptkbp:discoveredIn
|
1991
|
|
gptkbp:Entrez_Gene_ID
|
817
ENSG00000145349
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
brain
heart
|
|
gptkbp:fullName
|
Calcium/calmodulin-dependent protein kinase type II subunit delta
|
|
gptkbp:function
|
Involved in cardiac muscle contraction
Regulates synaptic plasticity
Serine/threonine-protein kinase involved in calcium signaling
|
|
gptkbp:gene
|
gptkb:CAMK2D
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
1454
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CAMK2D
|
|
gptkbp:length
|
535
|
|
gptkbp:locatedOnChromosome
|
4
|
|
gptkbp:location
|
4q26
|
|
gptkbp:molecularWeight
|
60 kDa
|
|
gptkbp:numberOfExons
|
23
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
mouse Camk2d
rat Camk2d
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:cAMP_signaling_pathway
calcium signaling pathway
|
|
gptkbp:PDB
|
2V7O
|
|
gptkbp:phosphorylates
|
various substrates including ion channels
|
|
gptkbp:postTranslationalModification
|
phosphorylation
autophosphorylation
|
|
gptkbp:proteinFamily
|
CaMKII family
|
|
gptkbp:regulates
|
activated by calcium/calmodulin
|
|
gptkbp:UniProtID
|
Q13557
|
|
gptkbp:bfsParent
|
gptkb:Familial_atrial_fibrillation
|
|
gptkbp:bfsLayer
|
7
|