|
gptkbp:instanceOf
|
gptkb:chemical_compound
|
|
gptkbp:ATCCode
|
gptkb:N02BA01
|
|
gptkbp:boilingPoint
|
140°C (decomposes)
|
|
gptkbp:CASNumber
|
50-78-2
|
|
gptkbp:color
|
white
|
|
gptkbp:contraindication
|
children with viral infections
patients with bleeding disorders
patients with peptic ulcer
|
|
gptkbp:derivedFrom
|
gptkb:salicylic_acid
|
|
gptkbp:drugClass
|
gptkb:NSAID
|
|
gptkbp:excretion
|
gptkb:kidney
|
|
gptkbp:firstSynthesized
|
gptkb:Felix_Hoffmann
|
|
gptkbp:flavor
|
bitter
|
|
gptkbp:GHSClassification
|
Acute Tox. 4
|
|
gptkbp:hasInChIKey
|
BSYNRYMUTXBXSQ-UHFFFAOYSA-N
|
|
gptkbp:hasMolecularFormula
|
C9H8O4
|
|
gptkbp:hasSMILES
|
CC(=O)Oc1ccccc1C(=O)O
|
|
gptkbp:hasUNII
|
R16CO5Y76E
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
C11216
|
|
gptkbp:isSolubleIn
|
gptkb:water
ethanol
|
|
gptkbp:IUPACName
|
2-acetyloxybenzoic acid
|
|
gptkbp:legalStatus
|
OTC (over-the-counter)
|
|
gptkbp:listedOn
|
gptkb:WHO_Model_List_of_Essential_Medicines
|
|
gptkbp:marketedAs
|
gptkb:Bayer
|
|
gptkbp:mechanismOfAction
|
inhibits cyclooxygenase (COX-1 and COX-2)
|
|
gptkbp:meltingPoint
|
135°C
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
180.16 g/mol
|
|
gptkbp:pregnancyCategory
|
D (US)
|
|
gptkbp:PubChem_CID
|
2244
DB00945
15365
|
|
gptkbp:refractiveIndex
|
1.504
|
|
gptkbp:riskFactor
|
H302 (harmful if swallowed)
|
|
gptkbp:routeOfAdministration
|
oral
rectal
|
|
gptkbp:sideEffect
|
bleeding
allergic reaction
gastrointestinal irritation
|
|
gptkbp:synonym
|
gptkb:Aspirin
gptkb:Acetylsalicylic_acid
|
|
gptkbp:usedFor
|
pain relief
anti-inflammatory
fever reduction
prevention of heart attack
prevention of stroke
antiplatelet
|
|
gptkbp:wasFirstSynthesizedIn
|
1897
|
|
gptkbp:bfsParent
|
gptkb:triclosan
|
|
gptkbp:bfsLayer
|
7
|