|
gptkbp:instanceOf
|
gptkb:drug
|
|
gptkbp:approvalYear
|
1986
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
N05BE01
|
|
gptkbp:brand
|
gptkb:Buspar
Ansial
Bespar
Buspimen
Buspinol
Buspirex
|
|
gptkbp:CASNumber
|
36505-84-7
|
|
gptkbp:chemicalFormula
|
C21H31N5O2
|
|
gptkbp:compatibleWith
|
gptkb:panic_disorder
psychosis
dependence
withdrawal symptoms
severe anxiety
sedation (minimal)
|
|
gptkbp:contraindication
|
hypersensitivity to buspirone
|
|
gptkbp:drugClass
|
gptkb:azapirone
benzodiazepine
|
|
gptkbp:eliminationHalfLife
|
2-3 hours
|
|
gptkbp:excretion
|
urine
feces
|
|
gptkbp:genericName
|
gptkb:buspirone
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Buspar
|
|
gptkbp:interactsWith
|
gptkb:milk
gptkb:rifampin
gptkb:MAO_inhibitors
gptkb:erythromycin
gptkb:ketoconazole
gptkb:verapamil
cimetidine
diltiazem
alcohol (may increase side effects)
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:manufacturer
|
gptkb:Bristol-Myers_Squibb
|
|
gptkbp:mechanismOfAction
|
dopamine D2 receptor antagonist
serotonin 5-HT1A receptor partial agonist
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
nausea
dizziness
headache
nervousness
lightheadedness
|
|
gptkbp:synonym
|
gptkb:buspirone_hydrochloride
|
|
gptkbp:usedFor
|
anxiety disorders
|
|
gptkbp:bfsParent
|
gptkb:Buspirone
gptkb:buspirone
|
|
gptkbp:bfsLayer
|
7
|