|
gptkbp:instanceOf
|
gptkb:Corticosteroid
|
|
gptkbp:approvedBy
|
gptkb:FDA
1981
|
|
gptkbp:ATCCode
|
gptkb:R01AD05
R03BA02
A07EA06
|
|
gptkbp:bioavailability
|
~10-20% (oral)
~39% (nasal)
|
|
gptkbp:brand
|
gptkb:Pulmicort
gptkb:Uceris
gptkb:Entocort
gptkb:Rhinocort
|
|
gptkbp:CASNumber
|
51333-22-3
|
|
gptkbp:discoveredBy
|
gptkb:AstraZeneca
|
|
gptkbp:eliminationHalfLife
|
2-3.6 hours
|
|
gptkbp:hasMolecularFormula
|
C25H34O6
|
|
gptkbp:KEGGID
|
D00245
|
|
gptkbp:legalStatus
|
Prescription only
|
|
gptkbp:mechanismOfAction
|
Glucocorticoid receptor agonist
|
|
gptkbp:MedlinePlusID
|
a608007
|
|
gptkbp:metabolism
|
Liver
|
|
gptkbp:pregnancyCategory
|
C (US)
B (Australia)
|
|
gptkbp:proteinBinding
|
85-90%
|
|
gptkbp:PubChem_CID
|
CHEMBL1433
4445532
5280725
DB01222
|
|
gptkbp:routeOfAdministration
|
gptkb:Oral
Rectal
Inhalation
Nasal
|
|
gptkbp:routesOfExcretion
|
Urine
Feces
|
|
gptkbp:sideEffect
|
gptkb:Nausea
Headache
Cough
Hoarseness
Oral thrush
Respiratory tract infection
|
|
gptkbp:UNII
|
Q3OKS62Q6X
|
|
gptkbp:usedFor
|
gptkb:Crohn's_disease
gptkb:Chronic_obstructive_pulmonary_disease
Ulcerative colitis
Allergic rhinitis
Asthma
Eosinophilic esophagitis
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
Yes
|
|
gptkbp:bfsParent
|
gptkb:Zentiva
|
|
gptkbp:bfsLayer
|
7
|
|
http://www.w3.org/2000/01/rdf-schema#label
|
Budesonide
|