|
gptkbp:instanceOf
|
gptkb:growth_factor
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:β-NGF
gptkb:nerve_growth_factor_beta
|
|
gptkbp:category
|
gptkb:signaling_molecule
gptkb:neurotrophin
|
|
gptkbp:discoveredBy
|
gptkb:Rita_Levi-Montalcini
gptkb:Stanley_Cohen
|
|
gptkbp:encodedBy
|
NGF gene
|
|
gptkbp:firstDescribed
|
1950s
|
|
gptkbp:foundIn
|
humans
mammals
|
|
gptkbp:function
|
promotes survival and differentiation of neurons
regulates growth, maintenance, and survival of nerve cells
|
|
gptkbp:involvedIn
|
pain signaling
development of peripheral nervous system
immune system modulation
|
|
gptkbp:locatedOnChromosome
|
chromosome 1p13.1 (human)
|
|
gptkbp:molecularWeight
|
~26 kDa
|
|
gptkbp:PDB
|
gptkb:1BET
|
|
gptkbp:promotion
|
neurite outgrowth
axon regeneration
|
|
gptkbp:recipient
|
gptkb:TrkA
gptkb:p75NTR
|
|
gptkbp:relatedTo
|
gptkb:peripheral_neuropathy
gptkb:Alzheimer's_disease
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:UniProtID
|
gptkb:P01138
|
|
gptkbp:usedIn
|
neuroscience research
|
|
gptkbp:bfsParent
|
gptkb:Beta-NGF
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Beta nerve growth factor
|