Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:BUB1B
|
| gptkbp:discoveredIn |
1998
|
| gptkbp:encodedBy |
gptkb:BUB1B_gene
|
| gptkbp:Entrez_Gene_ID |
701
|
| gptkbp:function |
mitotic checkpoint kinase
spindle assembly checkpoint protein |
| gptkbp:GO |
GO:0007094 (mitotic spindle assembly checkpoint)
|
| https://www.w3.org/2000/01/rdf-schema#label |
BUBR1
|
| gptkbp:interactsWith |
gptkb:CDC20
gptkb:BUB3 gptkb:MAD2 |
| gptkbp:involvedIn |
cell cycle regulation
mitosis chromosome segregation |
| gptkbp:length |
1050 amino acids
|
| gptkbp:locale |
gptkb:nucleus
kinetochore |
| gptkbp:locatedOnChromosome |
15q15
|
| gptkbp:molecularWeight |
120 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
Mosaic Variegated Aneuploidy syndrome |
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
gptkb:Drosophila_melanogaster
Mus musculus (mouse) |
| gptkbp:PDB |
2WVI
|
| gptkbp:phosphorylates |
Serine 676
Threonine 680 |
| gptkbp:regulates |
gptkb:APC/C_complex
|
| gptkbp:UniProtID |
O60566
|
| gptkbp:bfsParent |
gptkb:CDC20
gptkb:APC/C |
| gptkbp:bfsLayer |
7
|