BRCA2 mutation

GPTKB entity

Statements (61)
Predicate Object
gptkbp:instance_of gptkb:Genetics
gptkbp:associated_with gptkb:Oncology
ovarian cancer
gptkbp:can_be_passed_to offspring
gptkbp:can_lead_to gptkb:hereditary_breast_and_ovarian_cancer_syndrome
gptkbp:cause increased cancer risk
gptkbp:discovered_by gptkb:1995
https://www.w3.org/2000/01/rdf-schema#label BRCA2 mutation
gptkbp:included genetic databases
gptkbp:inherits_from autosomal dominant inheritance
gptkbp:investigates therapeutic interventions
gptkbp:investment fallopian tube cancer
peritoneal cancer
gptkbp:is_analyzed_in research studies
biomedical research
genetic predisposition
gptkbp:is_associated_with tumor suppressor gene
psychosocial impact
gptkbp:is_common_in certain families
gptkbp:is_considered risk-reducing options
gptkbp:is_considered_as hereditary risk factor
gptkbp:is_discussed_in support groups
genetic counseling
patient education materials
gptkbp:is_documented_in gptkb:literature
gptkbp:is_evaluated_by longitudinal studies
treatment options
gptkbp:is_examined_in population studies
gptkbp:is_explored_in genetic epidemiology
gptkbp:is_involved_in homologous recombination repair
gptkbp:is_linked_to gptkb:Oncology
gptkb:pancreatic_cancer
DNA repair mechanisms
increased mortality risk
survivorship issues
family planning decisions
male breast cancer
gptkbp:is_located_in chromosome 13
gptkbp:is_monitored_by oncologists
gptkbp:is_often_seen_in gptkb:Ashkenazi_Jewish_population
gptkbp:is_part_of cancer genetics
cancer prevention strategies
cancer research funding initiatives
cancer risk assessment tools
gptkbp:is_recognized_as significant health concern
gptkbp:is_recognized_by gptkb:guidelines
DNA sequencing
gptkbp:is_related_to gptkb:BRCA1_mutation
gptkbp:is_studied_in clinical trials
gptkbp:is_subject_to ethical considerations
public health initiatives
gptkbp:is_tested_for risk assessment
familial cancer syndromes
gptkbp:is_utilized_in personalized medicine
gptkbp:reported_by case studies
gptkbp:screenings genetic testing
gptkbp:treatment targeted therapy
preventive surgery
chemoprevention
gptkbp:bfsParent gptkb:Ovarian_Cancer
gptkbp:bfsLayer 5