hereditary breast and ovarian cancer syndrome
GPTKB entity
Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
|
| gptkbp:affects |
both men and women
|
| gptkbp:alsoKnownAs |
gptkb:HBOC
|
| gptkbp:associatedWith |
family history of breast or ovarian cancer
|
| gptkbp:diagnosedBy |
genetic testing
|
| gptkbp:firstDescribed |
1990s
|
| https://www.w3.org/2000/01/rdf-schema#label |
hereditary breast and ovarian cancer syndrome
|
| gptkbp:ICD-10_code |
Z15.0
|
| gptkbp:inheritsFrom |
autosomal dominant manner
|
| gptkbp:managedBy |
risk-reducing surgery
chemoprevention increased surveillance |
| gptkbp:MeSH_ID |
D054549
|
| gptkbp:mutationAssociatedWith |
gptkb:BRCA1_gene
gptkb:BRCA2_gene |
| gptkbp:OMIM |
604370
|
| gptkbp:prevalence |
about 1 in 400 people
|
| gptkbp:riskFactor |
gptkb:cancer
gptkb:fallopian_tube_cancer pancreatic cancer prostate cancer primary peritoneal cancer bilateral breast cancer early-onset breast cancer male breast cancer |
| gptkbp:bfsParent |
gptkb:BRCA1_mutation
|
| gptkbp:bfsLayer |
6
|