Statements (49)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:Oncology
|
| gptkbp:associated_with |
gptkb:BRCA1_gene
|
| gptkbp:clinical_trial |
checkpoint inhibitors
PARP inhibitors |
| gptkbp:community_health |
increased awareness needed
genetic testing accessibility disparities in healthcare access need for research funding importance of family history |
| gptkbp:demographics |
gptkb:Female
higher incidence in Ashkenazi Jews |
| gptkbp:diagnosis |
CT scan
ultrasound biopsy genetic counseling varies by stage early detection improves outcomes higher risk of recurrence potential for targeted treatment options |
| gptkbp:genetic_studies |
BRCA1 mutation testing
|
| https://www.w3.org/2000/01/rdf-schema#label |
BRCA1-related cancers
|
| gptkbp:includes |
gptkb:Oncology
ovarian cancer |
| gptkbp:is_involved_in |
Facing Our Risk of Cancer Empowered (FORCE)
BRCA1 Support Group |
| gptkbp:lifespan |
up to 44% for ovarian cancer
up to 72% for breast cancer |
| gptkbp:prevention |
prophylactic mastectomy
salpingo-oophorectomy |
| gptkbp:public_awareness |
gptkb:Breast_Cancer_Awareness_Month
gptkb:Ovarian_Cancer_Awareness_Month |
| gptkbp:research_focus |
gptkb:immunotherapy
targeted therapies |
| gptkbp:risk_factor |
gptkb:Genetics
family history |
| gptkbp:screenings |
gptkb:MRI
mammogram |
| gptkbp:symptoms |
fatigue
nausea weight loss changes in bowel habits abnormal vaginal bleeding lump in breast pain in the pelvic area |
| gptkbp:treatment |
gptkb:surgery
radiation therapy chemotherapy |
| gptkbp:bfsParent |
gptkb:BARD1_protein
|
| gptkbp:bfsLayer |
8
|