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gptkbp:instanceOf
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gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Bloom_syndrome_protein
gptkb:RECQL3
|
|
gptkbp:encodedBy
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gptkb:BLM_gene
|
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gptkbp:foundIn
|
gptkb:Homo_sapiens
|
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gptkbp:function
|
DNA repair
homologous recombination
DNA helicase activity
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gptkbp:GO
|
GO:0006281
GO:0004386
|
|
https://www.w3.org/2000/01/rdf-schema#label
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BLM protein
|
|
gptkbp:interactsWith
|
gptkb:RMI1
gptkb:RMI2
gptkb:TOP3A
|
|
gptkbp:involvedIn
|
genome stability
telomere maintenance
suppression of crossover during meiosis
|
|
gptkbp:length
|
1417 amino acids
|
|
gptkbp:locale
|
gptkb:nucleus
|
|
gptkbp:locatedOnChromosome
|
gptkb:15q26.1
|
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gptkbp:memberOf
|
gptkb:RecQ_helicase_family
|
|
gptkbp:molecularWeight
|
159 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Bloom_syndrome
increased cancer risk
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster
|
|
gptkbp:PDB
|
gptkb:4CGZ
|
|
gptkbp:regulates
|
sister chromatid exchange
|
|
gptkbp:structure
|
contains HRDC domain
contains RQC domain
contains helicase domain
|
|
gptkbp:UniProtID
|
P54132
|
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gptkbp:bfsParent
|
gptkb:FANCM
|
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gptkbp:bfsLayer
|
6
|