Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:binds |
acetylated lysine residues on histones
|
| gptkbp:contains |
gptkb:bromodomain
extra-terminal (ET) domain |
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:fullName |
Bromodomain and Extra-Terminal motif protein
|
| gptkbp:function |
regulation of gene expression
|
| https://www.w3.org/2000/01/rdf-schema#label |
BET protein
|
| gptkbp:involvedIn |
transcriptional regulation
|
| gptkbp:involves |
gptkb:cancer
gptkb:cardiovascular_disease neurological disorders inflammation |
| gptkbp:member |
BRD4
BRD2 BRD3 BRDT |
| gptkbp:structure |
one extra-terminal domain
two tandem bromodomains |
| gptkbp:studiedBy |
epigenetic therapy
|
| gptkbp:target |
BET inhibitors
|
| gptkbp:bfsParent |
gptkb:BET-BK
|
| gptkbp:bfsLayer |
7
|