Statements (31)
| Predicate | Object | 
|---|---|
| gptkbp:instanceOf | 
                                    
                                        
                                            gptkb:drug
                                        
                                         | 
                            
| gptkbp:alsoKnownAs | 
                                    
                                        
                                            gptkb:repotrectinib
                                        
                                         | 
                            
| gptkbp:approvalYear | 
                                    
                                        
                                            
                                            2023
                                        
                                        
                                         | 
                            
| gptkbp:approvedBy | 
                                    
                                        
                                            gptkb:FDA
                                        
                                         | 
                            
| gptkbp:ATCCode | 
                                    
                                        
                                            
                                            L01EX25
                                        
                                        
                                         | 
                            
| gptkbp:chemicalFormula | 
                                    
                                        
                                            
                                            C29H32N6O2
                                        
                                        
                                         | 
                            
| gptkbp:developer | 
                                    
                                        
                                            gptkb:Turning_Point_Therapeutics
                                        
                                         gptkb:Bristol_Myers_Squibb  | 
                            
| gptkbp:indication | 
                                    
                                        
                                            gptkb:non-small_cell_lung_cancer
                                        
                                         | 
                            
| gptkbp:legalStatus | 
                                    
                                        
                                            
                                            prescription only
                                        
                                        
                                         | 
                            
| gptkbp:mechanismOfAction | 
                                    
                                        
                                            gptkb:receptor_tyrosine_kinase
                                        
                                         | 
                            
| gptkbp:pregnancyCategory | 
                                    
                                        
                                            
                                            not recommended
                                        
                                        
                                         | 
                            
| gptkbp:prescriptionStatus | 
                                    
                                        
                                            
                                            Rx only
                                        
                                        
                                         | 
                            
| gptkbp:routeOfAdministration | 
                                    
                                        
                                            
                                            oral
                                        
                                        
                                         | 
                            
| gptkbp:sideEffect | 
                                    
                                        
                                            gptkb:peripheral_neuropathy
                                        
                                         gptkb:anemia nausea vomiting constipation dizziness fatigue dysgeusia increased liver enzymes  | 
                            
| gptkbp:target | 
                                    
                                        
                                            gptkb:ALK
                                        
                                         NTRK ROS1  | 
                            
| gptkbp:usedFor | 
                                    
                                        
                                            gptkb:ROS1-positive_non-small_cell_lung_cancer
                                        
                                         NTRK gene fusion-positive solid tumors  | 
                            
| gptkbp:bfsParent | 
                                    
                                        
                                            gptkb:repotrectinib
                                        
                                         | 
                            
| gptkbp:bfsLayer | 
                                    
                                        
                                            
                                            8
                                        
                                        
                                         | 
                            
| https://www.w3.org/2000/01/rdf-schema#label | 
                                    
                                        
                                            
                                            Augtyro
                                        
                                        
                                         |