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gptkbp:instanceOf
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gptkb:protein
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gptkbp:activity
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GTP binding
GTPase activity
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gptkbp:database
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gptkb:NCBI_Gene
gptkb:HGNC
gptkb:UniProt
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gptkbp:discoveredBy
|
1980s
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gptkbp:fullName
|
ADP-ribosylation factor GTPases
|
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gptkbp:function
|
regulation of actin cytoskeleton
regulation of vesicle trafficking
membrane remodeling
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|
https://www.w3.org/2000/01/rdf-schema#label
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Arf GTPases
|
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gptkbp:locale
|
gptkb:Golgi_apparatus
gptkb:plasma_membrane
endosomes
|
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gptkbp:member
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gptkb:ARF3
gptkb:ARF4
gptkb:ARF5
gptkb:ARF6
gptkb:ARL_proteins
gptkb:SAR_proteins
gptkb:ARF1
|
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gptkbp:orthologIn
|
found in eukaryotes
|
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gptkbp:posttranslational_modification
|
N-myristoylation
|
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gptkbp:proteinFamily
|
ARF gene family
|
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gptkbp:regulates
|
inactivated by GTPase-activating proteins (GAPs)
activated by guanine nucleotide exchange factors (GEFs)
|
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gptkbp:relatedTo
|
COPI vesicle formation
phospholipase D activation
phosphoinositide metabolism
|
|
gptkbp:structure
|
conserved GTP-binding domain
|
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gptkbp:superfamily
|
Ras superfamily of small GTPases
|
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gptkbp:bfsParent
|
gptkb:Ras_superfamily_GEFs
|
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gptkbp:bfsLayer
|
7
|